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Pediatric Use

BreathTek UBT is the only UBT approved for use in children ages 3 to 17 years

NASPGHAN* and ESPGHAN† recommend use of the UBT to confirm eradication of H. pylori infection in children1

94% of a joint NASPGHAN and ESPGHAN

94% of a joint NASPGHAN and ESPGHAN panel strongly agreed that the 13C-UBT is a reliable noninvasive test to determine H. pylori eradication2

pediatric 9-10

*North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

†European Society of Paediatric Gastroenterology, Hepatology and Nutrition.

Confirming eradication is important because of:

  • Poor adherence with medications3
  • Reinfection due to intrafamilial transmission3
  • Increasing antibiotic resistance1
    • In children treated with standard H. pylori therapy, eradication rates have been decreasing over time, in part because of increased antibiotic resistance1
    • Data suggest high rates of H. pylori antibiotic resistance in some pediatric populations1,4
References
  • Koletzko S, Jones NL, Goodman KJ, et al; H. pylori Working Groups of ESPGHAN, NASPGHAN. Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children. J Pediatr Gastroenterol Nutr. 2011;53(2):230-243.
  • Elitsur Y, Tolia V, Gilger MA, et al. Urea breath test in children: the United States prospective multicenter study. Helicobacter. 2009;14(2):134-140.
  • Moya DA, Crissinger KD. Helicobacter pylori persistence in children: distinguishing inadequate treatment, resistant organisms, and reinfection. Curr Gastroenterol Rep. 2012;14(3):236-242.
  • Tolia V, Brown W, El-Baba M, Lin C-H. Helicobacter pylori culture and antimicrobial susceptibility from pediatric patients in Michigan. Pediatr Infect Dis J. 2000;19(2):1167-1171.